Structure of PDB 4ofg Chain A

Receptor sequence
>4ofgA (length=142) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGE
VGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKV
NNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE
3D structure
PDB4ofg Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG A I465 L472 R473 F481 G482 E483 R484 A485 R492 T493 A494 I65 L72 R73 F81 G82 E83 R84 A85 R92 T93 A94
BS02 N2P A D479 Y480 D79 Y80
BS03 N2P A A402 D405 E432 A2 D5 E32
BS04 N2P A R528 M531 R128 M131
External links
PDB RCSB:4ofg, PDBe:4ofg, PDBj:4ofg
PDBsum4ofg
PubMed25646845
UniProtQ8I719|KGP_PLAF7 cGMP-dependent protein kinase (Gene Name=PKG)

[Back to BioLiP]