Structure of PDB 4oeg Chain A

Receptor sequence
>4oegA (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
PKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVS
ANRYLAMKEDGRLLASKSVTDECFFFERLESNNYNTYRSRKYTSWYVALK
RTGQYKLGSKTGPGQKAILFLPMS
3D structure
PDB4oeg Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDY A N27 R120 Q134 K135 A136 N8 R101 Q115 K116 A117 PDBbind-CN: -logKd/Ki=5.05,Kd=9.01uM
BS02 SUS A N27 K119 R120 K125 N8 K100 R101 K106 PDBbind-CN: -logKd/Ki=5.05,Kd=9.01uM
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:4oeg, PDBe:4oeg, PDBj:4oeg
PDBsum4oeg
PubMed24959968
UniProtP09038|FGF2_HUMAN Fibroblast growth factor 2 (Gene Name=FGF2)

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