Structure of PDB 4oee Chain A

Receptor sequence
>4oeeA (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
FPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERG
VVSIKGVSANRYLAMKEDGRLLASKSVTDECFFFERLESNNYNTYRSRKY
TSWYVALKRTGQYKLGSKTGPGQKAILFLPMS
3D structure
PDB4oee Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
ChainA
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDY A N27 R120 K125 Q134 K135 A136 N16 R109 K114 Q123 K124 A125 PDBbind-CN: -logKd/Ki=5.76,Kd=1.73uM
BS02 GNX A N27 K119 R120 K125 N16 K108 R109 K114 PDBbind-CN: -logKd/Ki=5.76,Kd=1.73uM
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:4oee, PDBe:4oee, PDBj:4oee
PDBsum4oee
PubMed24959968
UniProtP09038|FGF2_HUMAN Fibroblast growth factor 2 (Gene Name=FGF2)

[Back to BioLiP]