Structure of PDB 4oc7 Chain A

Receptor sequence
>4oc7A (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
DMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD
DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI
FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK
VYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT
PIDTFLMEMLEAP
3D structure
PDB4oc7 A natural-product switch for a dynamic protein interface.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F277 V280 K284 L294 V298 F450 E453 F32 V35 K39 L49 V53 F205 E208
BS02 2QO A I268 N306 F313 R316 L436 I23 N61 F68 R71 L191
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4oc7, PDBe:4oc7, PDBj:4oc7
PDBsum4oc7
PubMed24821627
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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