Structure of PDB 4o4t Chain A

Receptor sequence
>4o4tA (length=148) Species: 10090 (Mus musculus) [Search protein sequence]
RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVR
LSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG
3D structure
PDB4o4t Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A L41 F42 Y44 H64 K67 V68 V71 L92 H96 V101 F106 V109 L39 F40 Y42 H62 K65 V66 V69 L90 H94 V99 F104 V107
BS02 XE A F28 A29 F32 L56 F26 A27 F30 L54
BS03 XE A P20 M69 D73 P18 M67 D71
BS04 XE A P20 R66 P18 R64
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4o4t, PDBe:4o4t, PDBj:4o4t
PDBsum4o4t
PubMed25211169
UniProtQ9ER97|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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