Structure of PDB 4o3m Chain A

Receptor sequence
>4o3mA (length=613) Species: 9606 (Homo sapiens) [Search protein sequence]
KHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILM
PTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTG
DKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLL
ARFVIDEAHRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKIL
RPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSR
RECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIA
FGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDV
TRLKRLIMMEKDHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFN
PDFCKKHPDVSCDNCCKYKTRDVTDDVKSIVRFVQEHSPSGRFTMNMLVD
IFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQ
AIAYVMLGNKAQTVLNGNLKVDFMETENKVSQREEMVKKCLGELTEVCKS
LGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEV
ISVLQKYSEWTSP
3D structure
PDB4o3m Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0044237 cellular metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4o3m, PDBe:4o3m, PDBj:4o3m
PDBsum4o3m
PubMed24816114
UniProtP54132|BLM_HUMAN RecQ-like DNA helicase BLM (Gene Name=BLM)

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