Structure of PDB 4o35 Chain A

Receptor sequence
>4o35A (length=149) Species: 10090 (Mus musculus) [Search protein sequence]
MERPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFS
SPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVG
VRLSSWSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWD
3D structure
PDB4o35 Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A L41 F42 Y44 H64 K67 L92 H96 L103 W106 Y137 M144 L41 F42 Y44 H64 K67 L92 H96 L103 W106 Y137 M144
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4o35, PDBe:4o35, PDBj:4o35
PDBsum4o35
PubMed24914975
UniProtQ9ER97|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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