Structure of PDB 4o2w Chain A

Receptor sequence
>4o2wA (length=365) Species: 9606 (Homo sapiens) [Search protein sequence]
KCDVYLWGAGRHGQLAEAGRNVMVPAAAPSFSQAQQVICGQNCTFVIQAN
GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSM
ALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKH
SAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGL
NHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVA
CGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIED
VAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNV
RQISAGRCHSAAWTA
3D structure
PDB4o2w Crystal structure of the third RCC1-like domain of HERC1
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D4213 D4215 D218 D220
External links
PDB RCSB:4o2w, PDBe:4o2w, PDBj:4o2w
PDBsum4o2w
PubMed
UniProtQ15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 (Gene Name=HERC1)

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