Structure of PDB 4o29 Chain A

Receptor sequence
>4o29A (length=207) Species: 178306 (Pyrobaculum aerophilum str. IM2) [Search protein sequence]
ALMAKRLVEELERDGIVKSERVKRALLTVPREEFVLPEYRMMAYEDRPLP
LFAGATISAPHMVAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKG
RIYTIEIVKELAVFAAQNLERLGYWGVVEVYHGDGKKGLEKHAPFDAIIV
TAAADVIPPALIRQLKDGGVMVIPVEERLGQVLYKVVKRGDKIEKKAITY
VMFVPLR
3D structure
PDB4o29 Crystal structure of a protein repair methyltransferase from pyrococcus furiosus with its l-isoaspartyl peptide substrate
ChainA
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S56
Catalytic site (residue number reindexed from 1) S58
Enzyme Commision number 2.1.1.77: protein-L-isoaspartate(D-aspartate) O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A A53 T54 S56 G80 T81 S83 G84 Y85 H86 E104 I105 L109 G133 T149 L204 R205 A55 T56 S58 G82 T83 S85 G86 Y87 H88 E106 I107 L111 G135 T151 L206 R207
Gene Ontology
Molecular Function
GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168 methyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0030091 protein repair
GO:0032259 methylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4o29, PDBe:4o29, PDBj:4o29
PDBsum4o29
PubMed
UniProtQ8ZYN0|PIMT_PYRAE Protein-L-isoaspartate O-methyltransferase (Gene Name=pcm)

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