Structure of PDB 4o0m Chain A

Receptor sequence
>4o0mA (length=494) Species: 197221 (Thermosynechococcus vestitus BP-1) [Search protein sequence]
PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQF
LYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDAS
PDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASV
VRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRN
VLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSN
VRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGE
RALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHL
QIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITG
FFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRG
SWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDEKTE
3D structure
PDB4o0m An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC
ChainA
Resolution2.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A T290 G291 G293 K294 T295 L296 W331 R451 I472 T280 G281 G283 K284 T285 L286 W321 R441 I462
BS02 ATP A G50 K53 T54 L55 S90 F91 I240 G40 K43 T44 L45 S80 F81 I230
BS03 MG A T54 E79 T44 E69
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0044024 histone H2AS1 kinase activity
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0007623 circadian rhythm
GO:0016310 phosphorylation
GO:0042752 regulation of circadian rhythm
GO:0046777 protein autophosphorylation
GO:0048511 rhythmic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4o0m, PDBe:4o0m, PDBj:4o0m
PDBsum4o0m
PubMed24816106
UniProtQ79V60|KAIC_THEVB Circadian clock oscillator protein KaiC (Gene Name=kaiC)

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