Structure of PDB 4nzv Chain A

Receptor sequence
>4nzvA (length=329) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEA
EKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHD
WKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEA
LRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQG
REIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEAD
EKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNF
PGYVRVVYEEDSGILPDLMGEIDNLVKIE
3D structure
PDB4nzv DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.
ChainA
Resolution1.901 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D58 H180 H216 D63 H185 H221
BS02 MN A D14 H16 D58 H216 H218 D19 H21 D63 H221 H223
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0006259 DNA metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4nzv, PDBe:4nzv, PDBj:4nzv
PDBsum4nzv
PubMed24316220
UniProtQ9X1X0|MRE11_THEMA DNA double-strand break repair protein Mre11 (Gene Name=mre11)

[Back to BioLiP]