Structure of PDB 4nyv Chain A

Receptor sequence
>4nyvA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK
NPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSK
LAEVFEQEIDPVMQSL
3D structure
PDB4nyv Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand
ChainA
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 15E A P1110 V1115 N1168 V1174 P30 V35 N88 V94
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4nyv, PDBe:4nyv, PDBj:4nyv
PDBsum4nyv
PubMed
UniProtQ92793|CBP_HUMAN CREB-binding protein (Gene Name=CREBBP)

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