Structure of PDB 4nye Chain A

Receptor sequence
>4nyeA (length=235) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGKGVLNN
QISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSF
SKRFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYL
KEETRRINELLKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRL
WDADGNHMDKDVFRRGLGELTDVYEIVWEKLQELK
3D structure
PDB4nye Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg(2+), AIR and Asp.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A Y7 G9 K10 A11 K12 V83 I85 K122 D191 Y7 G9 K10 A11 K12 V83 I85 K122 D191
Gene Ontology
Molecular Function
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0009236 cobalamin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4nye, PDBe:4nye, PDBj:4nye
PDBsum4nye
PubMed24598753
UniProtQ07296|PUR7_STRPN Phosphoribosylaminoimidazole-succinocarboxamide synthase (Gene Name=purC)

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