Structure of PDB 4ny3 Chain A

Receptor sequence
>4ny3A (length=299) Species: 9606 (Homo sapiens) [Search protein sequence]
NFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVS
EAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVA
TVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGV
LRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGGVWGLDDFQFLPFIWG
SSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSN
QLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTS
3D structure
PDB4ny3 Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A.
ChainA
Resolution1.797 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I278 K286 G290 R293 M294 A297 E298 I255 K263 G267 R270 M271 A274 E275
Gene Ontology
Molecular Function
GO:0019211 phosphatase activator activity

View graph for
Molecular Function
External links
PDB RCSB:4ny3, PDBe:4ny3, PDBj:4ny3
PDBsum4ny3
PubMed25003389
UniProtQ15257|PTPA_HUMAN Serine/threonine-protein phosphatase 2A activator (Gene Name=PTPA)

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