Structure of PDB 4nxv Chain A

Receptor sequence
>4nxvA (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
RMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPL
RDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFF
LVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGS
LLDYVIRPAPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQ
YDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTA
SQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKV
NLFAELTPEEIDELGYTLYCSLSEPEVLLQ
3D structure
PDB4nxv Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A S189 H201 Q203 K326 S340 R342 K368 A382 S58 H70 Q72 K194 S208 R210 K236 A250 MOAD: Kd=3.8uM
PDBbind-CN: -logKd/Ki=5.42,Kd=3.8uM
Gene Ontology
Biological Process
GO:0007005 mitochondrion organization
Cellular Component
GO:0005741 mitochondrial outer membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4nxv, PDBe:4nxv, PDBj:4nxv
PDBsum4nxv
PubMed24515348
UniProtQ9NQG6|MID51_HUMAN Mitochondrial dynamics protein MIEF1 (Gene Name=MIEF1)

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