Structure of PDB 4nxq Chain A

Receptor sequence
>4nxqA (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
MGKVTHSIHIEKSDTAADTYGFSLSSVEEDGIRRLYVNSVKETGLASKKG
LKAGDEILEINNRAADALNSSMMEDFFSQPSVGLLVRTYPE
3D structure
PDB4nxq Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A T857 Y858 F860 S861 L862 S864 V865 N876 S908 M911 E912 F915 T19 Y20 F22 S23 L24 S26 V27 N38 S70 M73 E74 F77
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase-mediated signal transduction
GO:0090630 activation of GTPase activity

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Molecular Function
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Biological Process
External links
PDB RCSB:4nxq, PDBe:4nxq, PDBj:4nxq
PDBsum4nxq
PubMed27998539
UniProtQ13009|TIAM1_HUMAN Rho guanine nucleotide exchange factor TIAM1 (Gene Name=TIAM1)

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