Structure of PDB 4nxa Chain A

Receptor sequence
>4nxaA (length=153) Species: 9755 (Physeter catodon) [Search protein sequence]
VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLK
TEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIP
IKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELG
YQG
3D structure
PDB4nxa Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.-
1.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A F43 R45 H64 V68 L89 S92 H93 H97 I99 Y103 F43 R45 H64 V68 L89 S92 H93 H97 I99 Y103
BS02 ZN A H36 E38 H36 E38
BS03 ZN A E59 K62 E59 K62
BS04 XE A H82 A134 F138 H82 A134 F138
BS05 XE A G25 I28 L29 G65 V68 L69 G25 I28 L29 G65 V68 L69
BS06 XE A V17 H24 I28 L115 V17 H24 I28 L115
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0005344 oxygen carrier activity
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005737 cytoplasm
GO:0016528 sarcoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nxa, PDBe:4nxa, PDBj:4nxa
PDBsum4nxa
PubMed25211169
UniProtP02185|MYG_PHYMC Myoglobin (Gene Name=MB)

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