Structure of PDB 4nud Chain A

Receptor sequence
>4nudA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLN
LPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPG
DDIVLMAEALEKLFLQKINELPT
3D structure
PDB4nud Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NUD A W81 L92 N140 I146 W38 L49 N97 I103 MOAD: Ki<0.0845uM
PDBbind-CN: -logKd/Ki=7.07,Ki<0.0845uM
BindingDB: Ki=340nM
External links
PDB RCSB:4nud, PDBe:4nud, PDBj:4nud
PDBsum4nud
PubMed24144283
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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