Structure of PDB 4ntx Chain A

Receptor sequence
>4ntxA (length=410) Species: 9031 (Gallus gallus) [Search protein sequence]
VVWALCFMGSLALLALVCTNRIQYYFLYPHVTKLDEVAATRLTFPAVTFC
NLNEFRFSRVTKNDLYHAGELLALLNNRYEIPDTQTADEKQLEILQDKAN
FRNFKPKPFNMLEFYDRAGHDIREMLLSCFFRGEQCSPEDFKVVFTRYGK
CYTFNAGQDGKPRLITMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEA
GIKVQIHSQDEPPLIDQLGFGVAPGFQTFVSCQEQRLIYLPPPWGDCKAT
TGEFYDTYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECAD
PALDFLVEKDNEYCVCEMPCNVTRYGKELSMVKIPSKASAKYLAKKYNKS
EQYIGENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASI
LTVLELFDYA
3D structure
PDB4ntx X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
ChainA
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NA A T237 D238 T240 T193 D194 T196
BS02 AMR A E236 T237 D350 E354 E192 T193 D304 E308
Gene Ontology
Molecular Function
GO:0005272 sodium channel activity
GO:0015280 ligand-gated sodium channel activity
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ntx, PDBe:4ntx, PDBj:4ntx
PDBsum4ntx
PubMed24507937
UniProtQ1XA76|ASIC1_CHICK Acid-sensing ion channel 1 (Gene Name=ASIC1)

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