Structure of PDB 4nrs Chain A

Receptor sequence
>4nrsA (length=416) Species: 4839 (Rhizomucor miehei) [Search protein sequence]
SEFAFVKIASDGKGFTRYGEPYLIRGANYWQGMNLGADDCSGGDRKRMEL
EIKQMAEMGINNLRVMASSEGPDDQPYRMRPSMMPQPGKYNEGVFVGLDY
LLDTMDRYNMTAVMTLGNFWQWSGGFGQYVAWITGNQTIPYPVGDVTYDE
FTQFAARFYNDSEIAPKANKLFKDHIYTVQNRRNTVNGKIYKEDPVIMSW
QIANAPQEAPASWFEEISTFIKKGAPKHLVSAGLESKLDEYDFDRAHDHK
NIDYTTCHCWVENWGIYDPADPDGLPHANEYMHDFLESRSKWAAQLNKPI
VMEEFGMARDAWRNPEDETYKYLPSTPTSHKDEYYQKAFNQIVSLASNRS
FSGSNFWAYGGEGRSTYPPNPYGMVWLGDPPHEPHGWYSVYSNDTTVQII
KDYNANLLKVQKELSK
3D structure
PDB4nrs Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
ChainA
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.78: mannan endo-1,4-beta-mannosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A E232 W261 E235 W264
BS02 BMA A N201 W257 E301 W354 P377 E380 Y385 N204 W260 E304 W357 P380 E383 Y388
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004567 beta-mannosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016985 mannan endo-1,4-beta-mannosidase activity

View graph for
Molecular Function
External links
PDB RCSB:4nrs, PDBe:4nrs, PDBj:4nrs
PDBsum4nrs
PubMed25372687
UniProtA0A075C6T6

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