Structure of PDB 4npm Chain A

Receptor sequence
>4npmA (length=210) Species: 7955 (Danio rerio) [Search protein sequence]
EYEERRDAEARRVKSGIKQASIFTLEECARIEAKIDEVVAKADKGLYREH
TVDRAPLRNKYFFGEGYTQERLYSKGEVDDIPDWVHELVIDRLVTHGVIP
EGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFL
FKPIRVSEPVLHLPVRRGSVTVLSGYAADDITHCIRPQDIKERRAVIILR
KTRADAPRLD
3D structure
PDB4npm Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
ChainA
Resolution1.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.53: mRNA N(6)-methyladenine demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H135 D137 H197 H121 D123 H183
Gene Ontology
Molecular Function
GO:0035515 oxidative RNA demethylase activity
Biological Process
GO:0006397 mRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:4npm, PDBe:4npm, PDBj:4npm
PDBsum4npm
PubMed24561204
UniProtQ08BA6|ALKB5_DANRE RNA demethylase ALKBH5 (Gene Name=alkbh5)

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