Structure of PDB 4np3 Chain A

Receptor sequence
>4np3A (length=150) Species: 10090 (Mus musculus) [Search protein sequence]
NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLA
LSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYC
FNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI
3D structure
PDB4np3 Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
ChainA
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2L2 A N29 V30 E41 R82 V153 N154 R155 N6 V7 E18 R59 V130 N131 R132 MOAD: Kd=0.5mM
PDBbind-CN: -logKd/Ki=3.30,Kd=0.5mM
BindingDB: Kd=500000nM
Gene Ontology
Molecular Function
GO:0005540 hyaluronic acid binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4np3, PDBe:4np3, PDBj:4np3
PDBsum4np3
PubMed24606063
UniProtP15379|CD44_MOUSE CD44 antigen (Gene Name=Cd44)

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