Structure of PDB 4nod Chain A

Receptor sequence
>4nodA (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRR
3D structure
PDB4nod Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
ChainA
Resolution2.897 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L58 L65 T77 R140 M143 K146 Y162 Q179 K186 W189 L15 L22 T34 R97 M100 K103 Y119 Q136 K143 W146 PDBbind-CN: Kd=7.1nM
BS02 dna A R232 R233 R189 R190 PDBbind-CN: Kd=7.1nM
BS03 dna A Y57 T78 I81 A85 W88 R89 Y103 W107 R140 R157 N163 A167 F170 P178 Y14 T35 I38 A42 W45 R46 Y60 W64 R97 R114 N120 A124 F127 P135 PDBbind-CN: Kd=7.1nM
External links
PDB RCSB:4nod, PDBe:4nod, PDBj:4nod
PDBsum4nod
PubMed24435062
UniProtQ00059|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)

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