Structure of PDB 4nnc Chain A

Receptor sequence
>4nncA (length=483) Species: 626418 (Burkholderia glumae BGR1) [Search protein sequence]
TSLYITAAPIGAVPKFLDPFEATFIPSFLLEGFFDADRCASIAADLKTDG
WEVVPAGGRLLQVGHAQPIAAHFPKPWLAALSNKLARRIVLQLTTYGWIV
SEQGDLLWEHERQHHYLPPALIEAIEKESPALLKNMEEAGWIACAAGYWQ
AGKARSPYLPITPEAITEETIRSMRAGAAVVHLHTRDLSDRRRIEIPGLG
VVTVGSQRNQIVLDDYDAIVPMVKKREPAAILNLSTSVRGDRHGARSKLR
RAHLKFYDDVGSAPEVASLSPAAVVFQGGGGYDNAPDFLDAQFDHFERVG
TRPEVEVFNHAIVDNATSLYRDRLLRTGKPVLFMLVAGVDQYRRDPITGE
VEDDSLIARVVREEISSLLADESADSHRRAVELAIGQLRPVVERLRASFP
VSKISILLPGPMQNLLVDVALGLGLDGIRVGLEDGLTVNDARVPGGVRKA
RGTWEQVSLVREELLGRGATILTAAQVRDMFGL
3D structure
PDB4nnc Structural Basis for Bacterial Quorum Sensing-mediated Oxalogenesis.
ChainA
Resolution2.279 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.3.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CO A H222 H224 S275 E473 H182 H184 S235 E433
BS02 OXL A H224 S277 R279 Y322 H184 S237 R239 Y282
BS03 2KQ A R127 L131 K193 H222 H224 S275 S308 E346 F348 P449 P451 R469 E473 D474 L476 R87 L91 K153 H182 H184 S235 S268 E306 F308 P409 P411 R429 E433 D434 L436
Gene Ontology
Molecular Function
GO:0043720 3-keto-5-aminohexanoate cleavage activity

View graph for
Molecular Function
External links
PDB RCSB:4nnc, PDBe:4nnc, PDBj:4nnc
PDBsum4nnc
PubMed24616091
UniProtC5AJX5

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