Structure of PDB 4nm9 Chain A

Receptor sequence
>4nm9A (length=977) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence]
SMLNSELNTKIVNRGKEFFGSISGEKPSLFNKGAWMGKAMDWSMQNEQFK
IQMFRFVDVFPSLTTSKLLTEHIREYFGNEQDMPNKVLTSNIEEMARQFI
VGETTKEAVKNLEKLRKDGFAAVVDVLGEATLSEEEAEVYTNTYLELLEA
LKKEQGSWKGLPGKGGDPGLDWGHAPKVNIAVKPTALFCLANPQDFEGSV
VAILDRMRRIFKKVMELNGFLCIDMESYRHKEIILEVFRRLKLEYRDYPH
LGIVLQAYLKDNDKDLDDLLAWAKEHKVQISVRLVKGAYWDYETVKAKQN
DWEVPVWTIKAESDAAYERQARKILENHQICHFACASHNIRTISAVMEMA
RELNVPEDRYEFQVLYGMAEPVRKGILKVAGRIRLYAPYGNMVPGMGYLV
RRLLENTANESFLRQSFAEDAQIERLLEDPAVTVERERAARAAKGLGGLP
PFNNEAMVDFTRADHRAAFPKHIAQVRTQLGKTYPLFINGKEVRTNDLIP
TVNPNKPSEVLGQICQAGTTEVGDAIAAAKAAFPAWRDTDPRTRAEYLLK
AAQAARKRLFELSAWQVLEIGKQWDQAYADVTEAIDFLEYYAREMIRLGQ
PQRVGHAPGELNHYFYEPKGVAAVIAPWNFPLAISMGMASAAIVTGNCVV
FKPSGITSIIGWHLVELFREAGLPEGVFNFTPGRGSVMGDYLVDHPDISL
IAFTGSMETGLRIIERAAKVHPGQANVKKIISEMGGKNAIIIDDDADLDE
AVPHVLYSAFGFQGQKCSACSRVIVLDAVYDKFIERLVSMAKATKVGPSE
DPANYMGAVADDKAMKSIKEYAEIGKREGHVLYESPVPAGEGYFVPMTII
GGIKPEHRIAQEEIFGPVLAVMRAKDFDQAIEWANSTQFALTGGIFSRSP
EHLAKARREFRVGNLYINRNNTGALVERQPFGGARMSGVGTKAGGPDYLL
HFMDPRVVTENTMRRGFAPIEEDDDWV
3D structure
PDB4nm9 Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site.
ChainA
Resolution1.898 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N655 K678 E759 C793 E889 A969
Catalytic site (residue number reindexed from 1) N629 K652 E733 C767 E863 A943
Enzyme Commision number 1.2.1.88: L-glutamate gamma-semialdehyde dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A D244 M245 Q276 R303 V305 K306 G307 A308 Y309 W310 W327 T328 I329 K330 S333 A356 S357 H358 N359 L385 E425 S431 F432 D224 M225 Q256 R283 V285 K286 G287 A288 Y289 W290 W307 T308 I309 K310 S313 A336 S337 H338 N339 L365 E405 S411 F412
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003700 DNA-binding transcription factor activity
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0004657 proline dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006562 proline catabolic process
GO:0010133 proline catabolic process to glutamate
Cellular Component
GO:0005737 cytoplasm
GO:0009898 cytoplasmic side of plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nm9, PDBe:4nm9, PDBj:4nm9
PDBsum4nm9
PubMed24550478
UniProtQ746X3

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