Structure of PDB 4nl5 Chain A

Receptor sequence
>4nl5A (length=101) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PVVKINAIEVPAGAGPELEKRFAHRAHAVENSPGFLGFQLLRPVKGEERY
FVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLDVGGT
G
3D structure
PDB4nl5 Crystallographic and Spectroscopic Insights into Heme Degradation by Mycobacterium tuberculosis MhuD.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.99.57: heme oxygenase (mycobilin-producing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A N7 R22 F23 R26 A27 V30 F39 F63 W66 H75 P82 V83 N6 R21 F22 R25 A26 V29 F38 F62 W65 H74 P81 V82
BS02 CYN A N7 F23 V53 N6 F22 V52
Gene Ontology
Molecular Function
GO:0004392 heme oxygenase (decyclizing) activity
GO:0004497 monooxygenase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0042167 heme catabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nl5, PDBe:4nl5, PDBj:4nl5
PDBsum4nl5
PubMed24901029
UniProtP9WKH3|MHUD_MYCTU Heme oxygenase (mycobilin-producing) (Gene Name=mhuD)

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