Structure of PDB 4nkt Chain A

Receptor sequence
>4nktA (length=319) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
DMSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVA
FGSLESGLALKNSDMDLCVLMTIALQFYEELIAEGFEGKFLQRARIPIIK
LTSDTKNGFGASFQCAIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKH
WAKRKQINSPYFGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSPLKQEKI
VDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAYKFEPREKVVTFRR
PDGYLTKQEKGWTSRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAAS
RLLNSRSYPIPYDSLFEEA
3D structure
PDB4nkt A critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structure.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2KH A F88 S90 N171 K197 S211 Y212 H336 F51 S53 N127 K153 S167 Y168 H278 PDBbind-CN: -logKd/Ki=5.97,Kd=1.08uM
External links
PDB RCSB:4nkt, PDBe:4nkt, PDBj:4nkt
PDBsum4nkt
PubMed24322298
UniProtO13833|CID1_SCHPO Terminal uridylyltransferase cid1 (Gene Name=cid1)

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