Structure of PDB 4njr Chain A

Receptor sequence
>4njrA (length=425) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGG
RYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNG
FLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVI
PNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREH
GITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLN
AEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQR
SLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAG
FFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIR
ELAGSHDLAHLVKVLGAFYASSELP
3D structure
PDB4njr Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D236 E266 H401 D236 E266 H397
BS02 ZN A H82 D236 D307 H82 D236 D307
BS03 CO3 A H82 D236 E265 E266 H401 H82 D236 E265 E266 H397
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4njr, PDBe:4njr, PDBj:4njr
PDBsum4njr
PubMed24704201
UniProtQ9HYZ3|APEB_PSEAE Probable M18 family aminopeptidase 2 (Gene Name=apeB)

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