Structure of PDB 4ng4 Chain A

Receptor sequence
>4ng4A (length=384) Species: 227377 (Coxiella burnetii RSA 493) [Search protein sequence]
PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQK
ARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKPLINDWLKGVAVEPGQA
ILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAA
YAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLD
KVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSL
PLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQA
GTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFN
LTDQMSYVSTAGGAFLEFLEGKLPAIKILTQRAK
3D structure
PDB4ng4 Structural genomics for drug design against the pathogen Coxiella burnetii.
ChainA
Resolution2.78 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R39 K196 G349 G372
Catalytic site (residue number reindexed from 1) R35 K187 G340 G363
Enzyme Commision number 2.7.2.3: phosphoglycerate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D293 G319 F326 S327 T330 D284 G310 F317 S318 T321
BS02 ADP A G193 G194 S195 K200 N315 P317 E322 D350 T351 G184 G185 S186 K191 N306 P308 E313 D341 T342
Gene Ontology
Molecular Function
GO:0004618 phosphoglycerate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0043531 ADP binding
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ng4, PDBe:4ng4, PDBj:4ng4
PDBsum4ng4
PubMed26033498
UniProtQ83AU6|PGK_COXBU Phosphoglycerate kinase (Gene Name=pgk)

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