Structure of PDB 4nf8 Chain A

Receptor sequence
>4nf8A (length=285) Species: 10116 (Rattus norvegicus) [Search protein sequence]
STRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSP
GSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVSNKK
EWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGT
RITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYE
SAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGM
RKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQE
3D structure
PDB4nf8 Structural Insights into Competitive Antagonism in NMDA Receptors.
ChainA
Resolution1.856 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLY A F92 T126 R131 S179 S180 D224 F90 T122 R127 S175 S176 D220
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:4nf8, PDBe:4nf8, PDBj:4nf8
PDBsum4nf8
PubMed24462099
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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