Structure of PDB 4nef Chain A

Receptor sequence
>4nefA (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
SELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLG
IGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGA
ALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDE
RRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDH
WVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL
3D structure
PDB4nef X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C75 H80 C74 H79
Gene Ontology
Molecular Function
GO:0015267 channel activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nef, PDBe:4nef, PDBj:4nef
PDBsum4nef
PubMed24733887
UniProtP41181|AQP2_HUMAN Aquaporin-2 (Gene Name=AQP2)

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