Structure of PDB 4ncm Chain A

Receptor sequence
>4ncmA (length=163) Species: 392809 (Influenza A virus (A/Victoria/3/1975(H3N2))) [Search protein sequence]
SSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRA
TAILRKATRRLVQLIVSGKDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNF
VNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPS
TEMSMRGIRVSKM
3D structure
PDB4ncm Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2.
ChainA
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 704 A F323 F325 H357 E361 F404 M431 F3 F5 H37 E41 F84 M111 PDBbind-CN: -logKd/Ki=7.00,Kd=0.10uM
External links
PDB RCSB:4ncm, PDBe:4ncm, PDBj:4ncm
PDBsum4ncm
PubMed25019388
UniProtP31345|PB2_I75A3 Polymerase basic protein 2 (Gene Name=PB2)

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