Structure of PDB 4nao Chain A

Receptor sequence
>4naoA (length=282) Species: 5111 (Claviceps purpurea) [Search protein sequence]
GTKRFSIQSDPVEIHRAIVEDGVAIIEGFLTPEQVQKLNKDVDAPLKADR
EQFWLADFIPDHVARVHNLVDFSHCFRHEILNHELLHKICRLTFEESGDY
WLGYGAVIENGPGTTEQKWHRDQPRYPLVKEGPDAPEGMLNFFTALTDFD
AETGKTQYILGSNKRVELGEPDADHPIEYVGLKPGDTTIVSGKITHRGSD
NRSDKMRRAMPIMIIPSILTPFDATCHLSRELVETMTPLAQKMICRRSVM
IPAKTGIWCVNMREAGEQIGLKSNQRAKEDAE
3D structure
PDB4nao Cyclolization of d-lysergic Acid alkaloid peptides.
ChainA
Resolution1.649 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AKG A Q138 H141 F164 T177 H217 R228 Q117 H120 F143 T156 H196 R207
BS02 FE2 A H141 D143 H217 H120 D122 H196
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0009820 alkaloid metabolic process
GO:0035835 indole alkaloid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4nao, PDBe:4nao, PDBj:4nao
PDBsum4nao
PubMed24361048
UniProtG8GV69|EASH_CLAP2 Dioxygenase easH (Gene Name=easH)

[Back to BioLiP]