Structure of PDB 4n73 Chain A

Receptor sequence
>4n73A (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
HLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLS
QHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQE
TLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVH
3D structure
PDB4n73 Structure of REV-ERB beta Ligand-binding Domain Bound to a Porphyrin Antagonist.
ChainA
Resolution1.8662 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COH A L382 V383 C384 P385 M386 F405 F409 F443 M447 A479 G480 L483 M486 H568 L572 F575 L2 V3 C4 P5 M6 F25 F29 F63 M67 A99 G100 L103 M106 H188 L192 F195
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4n73, PDBe:4n73, PDBj:4n73
PDBsum4n73
PubMed24872411
UniProtQ14995|NR1D2_HUMAN Nuclear receptor subfamily 1 group D member 2 (Gene Name=NR1D2)

[Back to BioLiP]