Structure of PDB 4my6 Chain A

Receptor sequence
>4my6A (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
3D structure
PDB4my6 A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 3VH A Y16 W23 K69 N71 F77 Q79 W80 R81 V86 Y15 W22 K68 N70 F76 Q78 W79 R80 V85 PDBbind-CN: -logKd/Ki=5.62,Kd=2.4uM
BS02 3VH A Y16 D18 Y15 D17 PDBbind-CN: -logKd/Ki=5.62,Kd=2.4uM
External links
PDB RCSB:4my6, PDBe:4my6, PDBj:4my6
PDBsum4my6
PubMed25848013
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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