Structure of PDB 4mwz Chain A

Receptor sequence
>4mwzA (length=255) Species: 126793 (Plasmodium vivax Sal-1) [Search protein sequence]
KYLENNQYSDEGIKAYEFIFGEDYISSGGIIATTKILSDIQLDANSKVLD
IGSGLGGGCKYINEKYGAHVHGVDICEKMVTIAKLRNQDKAKIEFEAKDI
LKKDFPESTFDMIYSRDSILHLSYADKKMLFEKCYKWLKPNGILLITDYC
ADKIENWDEEFKAYIKKRKYTLMPIQEYGDLIKSCKFQNVEAKDISDYWL
ELLQLELSKLEEKKEEFLKVYSIKEYNSLKDGWTRKIKDTKRDLQKWGYF
KAQKM
3D structure
PDB4mwz Phosphoethanolamine N-methyl transferase is a Malarial drug target
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.103: phosphoethanolamine N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A Y16 I33 S34 G60 D82 I83 M87 D107 I108 R124 D125 S126 H129 Y8 I25 S26 G52 D74 I75 M79 D99 I100 R116 D117 S118 H121
Gene Ontology
Molecular Function
GO:0016740 transferase activity
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4mwz, PDBe:4mwz, PDBj:4mwz
PDBsum4mwz
PubMed
UniProtA5K867

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