Structure of PDB 4muv Chain A

Receptor sequence
>4muvA (length=142) Species: 266835 (Mesorhizobium japonicum MAFF 303099) [Search protein sequence]
GSQEVRRGDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVIC
RIGEPGDRMFFVVEGSVSVASPNPSELGPGAFFGEMALISGEPRSATVSA
ATTVSLLSLHSADFQMLCSSSPEIAEIFRKTALERRGADASA
3D structure
PDB4muv Determinants of ligand selectivity in a cyclic nucleotide-regulated potassium channel.
ChainA
Resolution1.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG A V282 F296 G297 E298 M299 A300 R307 S308 R348 D352 V69 F83 G84 E85 M86 A87 R94 S95 R135 D139 MOAD: Kd=336nM
PDBbind-CN: -logKd/Ki=5.76,Kd=1731nM
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity

View graph for
Molecular Function
External links
PDB RCSB:4muv, PDBe:4muv, PDBj:4muv
PDBsum4muv
PubMed24981229
UniProtQ98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

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