Structure of PDB 4mtz Chain A

Receptor sequence
>4mtzA (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
EEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAV
DRWQYGDSAVGRHRKVSPNCRFINGFYL
3D structure
PDB4mtz Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C63 C66 H83 C90 C43 C46 H63 C70
BS02 0BU A R62 C66 H67 S87 P88 N89 R42 C46 H47 S67 P68 N69
External links
PDB RCSB:4mtz, PDBe:4mtz, PDBj:4mtz
PDBsum4mtz
PubMed
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

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