Structure of PDB 4mtr Chain A

Receptor sequence
>4mtrA (length=119) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MRILHSMLRVADLEAALEFYTRALDMRLLRRRDYPEGRFTLAFVGYQDER
AAAALELTHNWDRDGYTQGDGYGHLAIEVEDAAVTCARARALGYRVTREV
IAFLEDPDGYKVELIQKGT
3D structure
PDB4mtr The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity.
ChainA
Resolution1.83 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H5 E56 H74 E122
Catalytic site (residue number reindexed from 1) H5 E56 H74 E113
Enzyme Commision number 4.4.1.5: lactoylglutathione lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H5 E56 H5 E56
BS02 ZN A H74 E122 H74 E113
Gene Ontology
Molecular Function
GO:0004462 lactoylglutathione lyase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4mtr, PDBe:4mtr, PDBj:4mtr
PDBsum4mtr
PubMed25411134
UniProtQ9I5L8

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