Structure of PDB 4msj Chain A

Receptor sequence
>4msjA (length=190) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
MAGTFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCG
KLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTH
PTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQT
IVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR
3D structure
PDB4msj Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H341 H343 D354 H98 H100 D111
BS02 ZN A H356 C397 H404 H406 H113 C154 H161 H163
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0061578 K63-linked deubiquitinase activity
GO:0140492 metal-dependent deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination
GO:0070536 protein K63-linked deubiquitination

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4msj, PDBe:4msj, PDBj:4msj
PDBsum4msj
PubMed24787148
UniProtQ9P371|SST2_SCHPO AMSH-like protease sst2 (Gene Name=sst2)

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