Structure of PDB 4mrh Chain A

Receptor sequence
>4mrhA (length=150) Species: 10090 (Mus musculus) [Search protein sequence]
NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLA
LSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYC
FNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI
3D structure
PDB4mrh Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
ChainA
Resolution1.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2CQ A R33 F38 F60 V137 T138 R10 F15 F37 V114 T115 MOAD: Kd=12.6mM
PDBbind-CN: -logKd/Ki=1.90,Kd=12.6mM
BindingDB: Kd=12600000nM
Gene Ontology
Molecular Function
GO:0005540 hyaluronic acid binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4mrh, PDBe:4mrh, PDBj:4mrh
PDBsum4mrh
PubMed24606063
UniProtP15379|CD44_MOUSE CD44 antigen (Gene Name=Cd44)

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