Structure of PDB 4mrd Chain A

Receptor sequence
>4mrdA (length=149) Species: 10090 (Mus musculus) [Search protein sequence]
QIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLAL
SKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCF
NASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI
3D structure
PDB4mrd Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BDP A Y83 I100 A102 Y59 I76 A78 PDBbind-CN: -logKd/Ki=3.37,Kd=428uM
BS02 BDP A C81 R82 I100 C57 R58 I76 PDBbind-CN: -logKd/Ki=3.37,Kd=428uM
Gene Ontology
Molecular Function
GO:0005540 hyaluronic acid binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4mrd, PDBe:4mrd, PDBj:4mrd
PDBsum4mrd
PubMed24606063
UniProtP15379|CD44_MOUSE CD44 antigen (Gene Name=Cd44)

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