Structure of PDB 4mn8 Chain A

Receptor sequence
>4mn8A (length=759) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVV
SVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQL
ILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGF
DYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSG
NQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQ
LTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLV
GPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGE
LPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIP
RGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLI
GKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSN
LTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLE
SLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKN
MQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNV
FTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLV
SLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASD
LMGNTDLCG
3D structure
PDB4mn8 Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex.
ChainA
Resolution3.062 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y148 R152 G174 M196 D220 R294 Y296 H316 S320 V340 H344 D393 D414 H417 S437 Q485 Y123 R127 G149 M171 D195 R269 Y271 H291 S295 V315 H319 D368 D389 H392 S412 Q460
External links
PDB RCSB:4mn8, PDBe:4mn8, PDBj:4mn8
PDBsum4mn8
PubMed24114786
UniProtQ9FL28|FLS2_ARATH LRR receptor-like serine/threonine-protein kinase FLS2 (Gene Name=FLS2)

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