Structure of PDB 4mjw Chain A

Receptor sequence
>4mjwA (length=532) Species: 1665 (Arthrobacter globiformis) [Search protein sequence]
MHIDNIENLSDREFDYIVVGGGSAGAAVAARLSEDPAVSVALVEAGPDDR
GVPEVLQLDRWMELLESGYDWDYPIEPQENGNSFMRHARAKVMGGCSSHN
SCIAFWAPREDLDEWEAKYGATGWNAEAAWPLYKRLETNEDAGPDAPHHG
DSGPVHLMNVPPKDPTGVALLDACEQAGIPRAKFNTGTTVVNGANFFQIN
RRADGTRSSSSVSYIHPIVEQENFTLLTGLRARQLVFDADRRCTGVDIVD
SAFGHTHRLTARNEVVLSTGAIDTPKLLMLSGIGPAAHLAEHGIEVLVDS
PGVGEHLQDHPEGVVQFEAKQPMVAESTQWWEIGIFTPTEDGLDRPDLMM
HYGSVPFDMNTLRHGYPTTENGFSLTPNVTHARSRGTVRLRSRDFRDKPM
VDPRYFTDPEGHDMRVMVAGIRKAREIAAQPAMAEWTGRELSPGVEAQTD
EELQDYIRKTHNTVYHPVGTVRMGAVEDEMSPLDPELRVKGVTGLRVADA
SVMPEHVTVNPNITVMMIGERCADLIRSARAG
3D structure
PDB4mjw Structure of choline oxidase in complex with the reaction product glycine betaine.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) I333 P377 N378 V464 H466 V509 N510
Catalytic site (residue number reindexed from 1) I333 P377 N378 V464 H466 V509 N510
Enzyme Commision number 1.1.3.17: choline oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G20 G22 S23 E44 A45 W71 R89 A90 G95 C96 H99 N100 S101 I103 R231 A232 T269 G270 D273 Y465 H466 A500 N510 P511 N512 V515 G20 G22 S23 E44 A45 W71 R89 A90 G95 C96 H99 N100 S101 I103 R231 A232 T269 G270 D273 Y465 H466 A500 N510 P511 N512 V515
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0033713 choline:oxygen 1-oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0019285 glycine betaine biosynthetic process from choline

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4mjw, PDBe:4mjw, PDBj:4mjw
PDBsum4mjw
PubMed24531474
UniProtQ7X2H8|CHOX_ARTGO Choline oxidase (Gene Name=codA)

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