Structure of PDB 4mgt Chain A

Receptor sequence
>4mgtA (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]
MSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPAKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELASPIASVSFGASRDFVFRHKDSPSRR
VAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLG
3D structure
PDB4mgt The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R98 W105 R44 W51
BS02 dna A R98 C169 R198 R241 K242 R44 C115 R142 R181 K182
BS03 MG A H171 D173 H236 H117 D119 H176
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:4mgt, PDBe:4mgt, PDBj:4mgt
PDBsum4mgt
PubMed
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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