Structure of PDB 4mgb Chain A

Receptor sequence
>4mgbA (length=240) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4mgb Structural and functional profiling of environmental ligands for estrogen receptors.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 Q375 V376 E380 D538 L539 E542 I54 K58 L68 Q71 V72 E76 D230 L231 E234
BS02 XDH A L346 L349 A350 L387 M388 F404 I424 F425 G521 H524 L42 L45 A46 L83 M84 F100 I118 F119 G213 H216 PDBbind-CN: -logKd/Ki=5.44,Kd=3.67uM
External links
PDB RCSB:4mgb, PDBe:4mgb, PDBj:4mgb
PDBsum4mgb
PubMed25260197
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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