Structure of PDB 4mga Chain A

Receptor sequence
>4mgaA (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB4mga Structural and functional profiling of environmental ligands for estrogen receptors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 D538 L539 E542 I54 K58 L68 V72 E76 D230 L231 E234
BS02 27L A E353 L391 E49 L87 PDBbind-CN: -logKd/Ki=5.86,Kd=1.37uM
External links
PDB RCSB:4mga, PDBe:4mga, PDBj:4mga
PDBsum4mga
PubMed25260197
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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