Structure of PDB 4mg2 Chain A

Receptor sequence
>4mg2A (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
MSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVAGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELASPIASVSFGASRDFVFRHKDSVAVV
RLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLM
3D structure
PDB4mg2 The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R98 C169 R198 R241 K242 R44 C115 R142 R177 K178
BS02 MG A H171 D173 H236 H117 D119 H172
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:4mg2, PDBe:4mg2, PDBj:4mg2
PDBsum4mg2
PubMed
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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