Structure of PDB 4mfq Chain A

Receptor sequence
>4mfqA (length=323) Species: 1867 (Actinoplanes teichomyceticus) [Search protein sequence]
MDPETVRIALGLEERTAAWLTELDELGPPAEPVRLPRGEEARDLLRRLEV
PELDAEEIVAAAPDPDRDPALWWLLERTHHAIVRHMGDHRAKPRGGPPLP
YEGGAAARYFHVYVFLATVPAVRRFHAERGIPDEVGWETLTQLGELVAIH
RRKYGQGGMNMQWWTTYHLRGILYRLGRLQFSLATGKDGTPHLGLAVPEW
GGPLLPKAYDESLHRARPFFDRHFPEHGARVAWGSSWMLDPQLEEYLTED
SNIIQLARFWTLTDSAPEPGNADGDSSILEFVFRYNGQPLDELPQRSSLE
RAVIAHLKAGRHWHMRTGFVKLP
3D structure
PDB4mfq Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K92 P93 W163 Y167 S276 E280 F281 K92 P93 W163 Y167 S276 E280 F281
BS02 COA A V197 P203 L204 S236 W237 S251 N252 I253 F281 S297 S298 L299 V197 P203 L204 S236 W237 S251 N252 I253 F281 S297 S298 L299
BS03 GCS A M161 W163 W164 V197 F281 M161 W163 W164 V197 F281
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4mfq, PDBe:4mfq, PDBj:4mfq
PDBsum4mfq
PubMed25095906
UniProtQ70AY4

[Back to BioLiP]