Structure of PDB 4mdr Chain A

Receptor sequence
>4mdrA (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
NEVFLAVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEF
SVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRY
QLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHL
PLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPL
GLGPASLSFELPRHTCSGLQVRFLRLAPHKWVRHLSHSDAYVIRI
3D structure
PDB4mdr Structural and Functional Characterization of Cargo-Binding Sites on the mu 4-Subunit of Adaptor Protein Complex 4.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A S254 F255 H256 S257 L261 E265 T280 R283 S70 F71 H72 S73 L77 E81 T96 R99
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process

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Cellular Component
External links
PDB RCSB:4mdr, PDBe:4mdr, PDBj:4mdr
PDBsum4mdr
PubMed24498434
UniProtO00189|AP4M1_HUMAN AP-4 complex subunit mu-1 (Gene Name=AP4M1)

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